Dr. Chidolue Fortunatus Ezebuo
Dr. Chidolue Fortunatus Ezebuo is a LECTURER I in PHARMACEUTICAL AND MEDICINAL CHEMISTRY Department, Faculty Of Pharmaceutical Sciences in Nnamdi Azikiwe University
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Staff Profile
Fortunatus C. Ezebuo is a faculty member in the Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka. Before he joined Nnamdi Azikiwe University, he served as a faculty member in the Department of Biochemistry at Chrisland University, Abeokuta from October 2018 to March 2019. Again, he worked as a voluntary research/teaching assistant in the Department of Biochemistry at Chukwuemeka Odumegwu Ojukwu University from March 2012 to September 2018. Fortunatus’s research interest focuses on computer-aided drug design/discovery, and molecular biophysics. He is a Member of the American Chemical Society (October 2022 to date). Fortunatus is happily married to Goodness and both have two children
Personal Information
Email: | |
Phone: | |
Address: | Pharmaceutical And Medicinal Chemistry, Faculty Of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka. |
Faculty/Unit: | FACULTY OF PHARMACEUTICAL SCIENCES |
Department/Sub-Unit: | PHARMACEUTICAL AND MEDICINAL CHEMISTRY |
Social Profiles
Academic Qualifications
| Degrees / Basic Certificates | |
|---|---|
| 1 | Nnamdi Azikiwe University, Awka. (Doctor of Philosophy, August, 2018) June, 2015 to August, 2018 P.hD Pharmaceutical And Medicinal Chemistry |
| 2 | University Of Nigeria, Nsukka. (Master Degree, January, 2013) June, 2010 to January, 2012 M.Sc Enzymology And Protein Structure |
| 3 | Anambra Sate University, Uli. (Bachelor Degree, November, 2008) October, 2004 to November, 2008 B.Sc Biochemistry |
Relevant/Working Experience
| 1 | Lecturer I, Nnamdi Azikiwe University, Awka October, 2022 to Present |
| 2 | Lecturer II, Nnamdi Azikiwe University, Awka April, 2019 to September, 2022 |
| 3 | Lecturer II, Chrisland University, Abeokuta October, 2018 to March, 2019 |
| 4 | Researcher/Tutor, Chukwuemeka Odumegwu Ojukwu University March, 2012 to September, 2018 |
Creative Output
| Book Chapters | |
|---|---|
| 1 | Ezebuo F.C., Kushwaha P.P., Singh A.K., Kumar S., Singh P. (2019, June) In-silico Methods Of Drug Design: Molecular Simulations And Free Energy Calculations In: Kumar S., Egbuna C. (eds) Phytochemistry: An in-silico and in-vitro Update. Springer, Singapore., pp 521-533 |
| Journal Articles | |
| 1 | Madeleine I. Ezeh, Onyinyechi E. Okonkwo, Innocent N. Okpoli, Chima E. Orji, Benjamin U. Modozie, Augustine C. Onyema, Fortunatus C. Ezebuo. (2022, September), "Chemoinformatic Design and Profiling of Derivatives of Dasabuvir, Efavirenz, and Tipranavir as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase and Methyltransferase", ACS Omega, Vol. 7, (Issue 37), pp 33330–33348 |
| 2 | Ezebuo, F.C., and Uzochukwu, I.C. (2020, September), "Drug Repurposing For Schistosomiasis: Molecular Docking And Dynamics Investigations", JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS, Vol. 14, pp 1-15 |
| 3 | Stefanik, M., Valdes, J.J., Ezebuo, F.C., Haviernik, J., Uzochukwu, I.C., Fojtikova, M., Salat, J., Ludek Eyer, L and Ruzek, D. (2020, April), "FDA-Approved Drugs Efavirenz, Tipranavir, And Dasabuvir Inhibit Replication Of Multiple Flaviviruses In Vero Cells", Microorganisms, Vol. 8, (Issue 4), pp 599 |
| 4 | Ezebuo, F.C., and Uzochukwu, I.C. (2020, September), "Schistosomal Sulfotransferase Interaction With Oxamniquine Involves Hybrid Mechanism Of Induced-fit And Conformational Selection", Curr Comput Aided Drug Des., Vol. 16, (Issue 4), pp 451 - 459 |
| 5 | Uzochukwu IC., Olubiyi, OO., Ezebuo, FC., Obinwa, IC., Ajaegbu, EE., 1 Eze, PM., Or- ji, CE., Onuoha, MC., Ejiofor, II and Nkechukwu, M. (2016, December), "Ending The Ebola Virus Scourge: A Case For Natural Products", Open Access Journal of Pharmaceutical Research, Vol. 1, (Issue 1), pp 000105 |
| 6 | Ezebuo F. C., Lukong C.B., Uzochukwu,I. C, Okafor I.N. (2016, January), "IN SILICO INVESTIGATIONS REVEALED FOUR POTENTIAL COLON CANCER DRUGS FROM PHYTOCHEMICALS IN ZINGIBER OFFICINALE", International Journal of Phytomedicine, Vol. 8, (Issue 3), pp 435-443 |
| 7 | Ifemeje, J.C., Egbuna, C., Eziokwudiaso, J.O, Ezebuo, F.C. (2014, June), "Determination Of The Anti-nutrient Composition Of Ocimum Gratissimum, Corchorus Olitorius, Murraya Koenigii Spreng And Cucurbita Maxima", International Journal of Innovation and Scientific Research, Vol. 3, (Issue 2), pp 127–133 |
| 8 | Okafor I.N, Ezebuo F.C, Azodo N.T. (2014, July), "Effect Of Moringa Oleifera Leaf Protein Concentrate Supplemented Feed On Growth And Nutritional Parameters In Broilers", World Applied Sciences Journal, Vol. 32, (Issue 1), pp 133-138 |
| 9 | Akubugwo, E.I, Okafor I. N, Ezebuo, F.C, Nwaka, A.C. (2014, April), "Nutritional Status Of Preschool Aged Children In Anambra State, Nigeria", IOSR Journal of Pharmacy and Biological Sciences, Vol. 9, pp 01-08 |
| 10 | Okafor I.N, Ezebuo F.C. (2014, October), "Proximate Analysis And Antinutrient Composition Of Poultry Feed Containing Two Replacement Levels Of Mucuna Pruriens For Soy Bean Meal", World Applied Sciences Journal, Vol. 32, (Issue 2), pp 201-206 |
| 11 | Lukong C.B, Ezebuo F.C, Onumaerosim M.N. (2014, December), "Electrophoretic Characterization Of Water Soluble Seed Proteins And The Relationship Between Some Legume Species In Nigeria", World Journal of Agricultural Sciences, Vol. 10, (Issue 4), pp 154-162 |
| 12 | Ezebuo, F.C., Eze S.O.O Lukong, C.B and Chilaka, F.C. (2013, October), "Interaction Of Normal And Sickle Hemoglobins For Sodium Dodecylsulphate And Hydrogen Peroxide At PH 5.0 And 7.2", ISRN Hematol ., Vol. 2013, pp 629640 |
| 13 | Akubugwo E I, Okafor I N, Ezebuo F C, Nwaka A C, and Okafor S O. (2013, October), "Prevalence Of Stunting Amongst Preschool Age Children From Selected Towns In Anambra South Senatorial Zone", nternational Journal of Life Sciences Biotechnology and Pharma Research,, Vol. 2, (Issue 4), pp 127-136 |
| 14 | Fortunatus C. EZEBUO, Ferdinand C. CHILAKA, Sabinus Oscar O. EZE. (2012, June), "Ligands Induced Formation Of Heme Radicals At PH’s 5.0 And 7.2: Implication In Malaria Resistance", Advances in Bioresearch, Vol. 3, (Issue 2), pp 66 - 74 |
| 15 | Lukong C. B, Ezebuo F. C, Verla A. W.. (2012, September), "Characterization Of The Major Essential Elements In The Haemolymph Of The Giant African Land Snail (Achatina Achatina) During Aestivation", Biosci Biotech Res Asia, Vol. 9, (Issue 2) |
| 16 | F C Ezebuo, S O O Eze, F C Chilaka. (2012, December), "Effects Of Sodium Dodecyl Sulphate On Enhancement Of Lipoxygenase Activity Of Hemoglobin", Indian J Exp Biol., Vol. 50, (Issue 12), pp 847-52 |
| Dissertations | |
| 1 | Fortunatus C. EZEBUO. (2018, August), "DISCOVERY OF APPROVED DRUGS WITH POSSIBLE MULTITARGET INHIBITORY ACTIVITIES AGAINST SCHISTOSOMA SPECIES". |
| 2 | Fortunatus C. Ezebuo. (2011, June), "EFFECTS OF SODIUM DODECYL SULPHATE, HYDROGEN PEROXIDE AND LINOLEIC ACID ON NORMAL AND SICKLE HAEMOGLOBINS". |
| Conference Papers | |
| 1 | Stefanik, M., Ezebuo, F.C., Haviernik, J., Uzochukwu, I.C., Fojtikova, M., Salat, J., Lu- dek Eyer, L and Ruzek, D. (2020, June), "FDA Approved Drugs Efavirenz, Tipranavir, And Dasabuvir Inhibit Replication Of Multiple Flaviviruses In Vitro", Proceedings of Viruses 2020â€â€Novel Concepts in Virology, Vol. 50, (Issue 1), pp 6 |
| 2 | Irene N. Okafor, Fortunatus C. Ezebuo, Colin B. Lukong. (2018, July), "Computational Investigation On Potential Inhibitors Of Snake Venom Phospholipase-A2 From Phytochemicals In Uvaria Chamae, Euphorbia Hirta, Portulaca Oleracea And Chromolaena Odorata", |
| 3 | Fortunatus C. Ezebuo, Ikemefuna C. Uzochukwu. (2017, July), "Effects Of Potential Anti-schistosomiasis Drugs On The Longevity And Survival Rates Of Drosophila Melanogaster", |
| 4 | Uzochukwu Ikemefuna C., Olubiyi, Olujide O., Ezebuo, Fortunatus C., Obinwa, Ifeyinwa C., Ajaegbu, Eze E., Eze, Peter M., Orji, Chima E., Onuoha, Maxwe. (2015, October), "Drug Repurposing For Ebola: In Silico Determination Of Binding Affinities Against Four Viral Proteins", The UNESCO-Merck Serono Africa Research Summit (MARS) 2015 held at Geneva, Switzerland |
Academic Leadership Qualities
| Grants | |
|---|---|
| 1 | Awardee: "2020 African-German Network of Excellence in Science (AGNES) Grant for Junior Researchers" (March, 2021). Completed sponsored grant by African-German Network of Excellence in Science |
| 2 | Awardee: "Corporate Partnership Programme Registration Fee Waive to participate in virtual EMBL Course: Computing Skills For Reproducible Research: Software Carpentry" (October, 2020 to October, 2020). Completed sponsored grant by European Molecular Biology Laboratory (EMBL) |
| 3 | Awardee: "5th Workshop on Advanced Techniques for Scientific Programming and Management of Open Source Software Packages" (January, 2017 to March, 2017). Completed sponsored grant by The International Centre for Theoretical Physics (ICTP) |
| 4 | Awardee: "ICTS-ICTP Winter School on Quantitative Systems Biology (QSB2017)" (September, 2017 to December, 2017). Completed sponsored grant by The International Centre for Theoretical Physics (ICTP) |
| 5 | Awardee: "DrosAfrica-ICGEB Workshop on Drosophila melanogaster in Biomedical Research: Low-Cost and Profitable" (July, 2017 to July, 2017). Completed sponsored grant by DrosAfrica |
| 6 | Collaborator: "Drug repurposing for lassa fever virus: A new treatment option" (January, 2020). Ongoing sponsored grant by National Research Fund (NRF) Intervention, Tertiary Education Trust Fund (TETFund) |
| Reviewerships | |
| 1 | Reviewer, "Neurological Research" (January, 2024) |
| 2 | Reviewer, "Current Medical Research & Opinion" (October, 2022) |
| 3 | Reviewer, "Future Medicinal Chemistry" (November, 2022) |
| 4 | Reviewer, "Journal of Biomolecular Structure and Dynamics" (November, 2020) |
| Contributions to the University/Society | |
| 1 | Member of Examination/Time table Committee, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (May, 2021) |
| 2 | Member of Consultancy Committee, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (May, 2021) |
| 3 | Member, TETFUND Center of Excellence for Biomedical, Engineering, Agriculture and Translation Studie, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (May, 2021) |
| 4 | Faculty Representative, Ekwueme Center for Multidisciplinary Research Committee, "Nnamdi Azikiwe University, Awka" (January, 2020) |
| 5 | Secretary, ICT/Library Committee, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (May, 2019 to May, 2021) |
| 6 | Member of Examination/Time table Committee, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (May, 2019 to May, 2021) |
| 7 | Departmental Examination Officer, "Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka" (April, 2019) |
Membership of Professional/Relevant Bodies
| 1 | Full Member, "American Chemical Society" - 32999167 (member since 2022), https://www.acs.org/content/acs/en.html |
Relevant Events Attended
| Other Events | |
|---|---|
| 1 | "Computing Skills For Reproducible Research: Software Carpentry - Virtual", (European Molecular Biology Laboratory (EMBL)), 19th October, 2020 to 23rd October, 2020; Heidelberg, Germany |
| 2 | "Winter School On Quantitative Systems Biology", (International Centre for Theoretical Physics (ICTP), Italy in collaboration with International Centre for Theoretical Sciences (ICTS) of the Tata Institute of Fundamental Research (TIFR), Bangalore, India), 4th December, 2017 to 22nd December, 2017; Bangalore, India |
| 3 | "DrosAfrica-ICGEB Workshop "Drosophila Melanogaster In Biomedical Research: Low-cost And Profitable"", (DrosAfrica-ICGEB), 17th July, 2017 to 28th July, 2017; Ibandan, Nigeria |
| 4 | "5th Workshop On Advanced Techniques For Scientific Programming And Management Of Open Source Software Packages", (International Centre for Theoretical Physics (ICTP), Italy in collaboration with Sharif University of Technology, Tehran), 4th March, 2017 to 15th March, 2017; Tehran, Iran |
| 5 | "Workshop On Programming For Biomedical And Pharmaceutical Scientists", (Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.), 25th February, 2015 to 27th February, 2015; Agulu, Nigeria |
| 6 | "Bioinformatics Workshop On Molecular Docking And Drug Design", (Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.), 4th July, 2014 to 4th July, 2014; Agulu, Nigeria |
| 7 | "Bioinformatics Workshop On Sequence Analysis", (Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.), 28th March, 2014 to 28th March, 2014; Agulu, Nigeria |