Prof. Dozie Callistus Nwakile
Prof. Dozie Callistus Nwakile is a PROFESSOR in PHARMACEUTICS AND PHARMACEUTICAL TECHNOLOGY Department, Faculty Of Pharmaceutical Sciences in Nnamdi Azikiwe University
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Personal Information
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Address: | Pharmaceutics And Pharmaceutical Technology, Faculty Of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka. |
Faculty/Unit: | FACULTY OF PHARMACEUTICAL SCIENCES |
Department/Sub-Unit: | PHARMACEUTICS AND PHARMACEUTICAL TECHNOLOGY |
Social Profiles
Interest Areas
Academic Qualifications
Relevant/Working Experience
| 1 | Head of Department, Department of Pharmaceutics and Pharmaceutical Technology September, 2018 to February, 2024 |
| 2 | Lecturer, Depart of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University Awka March, 2010 to Present |
| 3 | Superintendent Pharmacist, Jonachuks Pharmacy Nig Limited September, 2006 to March, 2010 |
| 4 | Intern Pharmacist, Faculty of Pharmaceutical Sciences University of Nigeria Nsukka February, 2005 to February, 2006 |
| 5 | Lecturer, Department of Laboratory Sciences, University of Nigeria Nsukka January, 2005 to December, 2006 |
Creative Output
| Journal Articles | |
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| 1 | O. D. Ezechukwu, C. D. Nwakile, C. E. Umeyor, O. C. Dozie-Nwakile, E. M. Uronnachi, U. M. Okezie, C. J. Ike, J. C. Obasi, I. J. Okeke, A. N. Oli. (2023, February), "HERBAL BASED ANTI-MICROBIAL BOOSTER FOR THE TREATMENT OF RESISTANT MYCOBACTERIUM TUBERCULOSIS", International Journal of Pharmaceutical Sciences and Research, Vol. 14, (Issue 2), pp 711-718 |
| 2 | Somtochukwu R Ewuzie, Calistus D Nwakile, Emmanuel M Uronnachi, Chukwuebuka E Umeyor, Ogechukwu C Dozie-Nwakile. (2023, November), "A Review of gentamicin sulphate oral preparation containing natural oil (pumpkin seed oil) for systemic indication", Somtochukwu R Ewuzie et al www.ijetst.in Page 32 IJETST- Vol.||10||Issue||11||Pages 8032-8042||November||ISSN 2348-9480 2023 International Journal of Emerging Trends in Science and Technology, Vol. 10, (Issue 11), pp 830 - 842 |
| 3 | Ikeotuonye CB, Uronnachi EM, Nwakile CD, Attama AA. (2023, October), "Ocimum Gratissimum essential oil: A review of extraction methods, phytochemical constituents, pharmacological uses and formulation approaches", JCBR, Vol. 03, (Issue 05), pp 1178 - 1196 |
| 4 | Calistus Dozie Nwakile, Ogechukwu Calista Dozie-Nwakile, Confidence Ogonna Ugama, Josephat Chekwube Obasi, Ifeanyi Justin Okeke, Ikenna Kingsley Uchendu, Uduma Eke Osonwa, Ifeanyi Eric Okoye, Anthony Amachi Attama and Vincent Chima Okore. (2023, March), "Pro-Drug of Gentamicin Sulphate for Localized Indications: Preliminary Investigation", Journal of Drug Design and Discovery Research, Vol. 4, (Issue 01), pp 175-182 |
| 5 | Onyinye Okpalaku, Emmanuel Uronnachi, Eric Okoye, Chukwuebuka Umeyor, Calistus Nwakile, Tochukwu Okeke, Anthony Attama. (2022, March), "Evaluating some Essential Oils-Based and Coconut Oil Nanoemulgels for the Management of Rheumatoid Arthritis", Letters in Applied NanoBioScience, Vol. 12, (Issue 3), pp 1-24 |
| 6 | Emmanuel Maduabuchi Uronnachi, Anthony Attama, Franklin Kenechukwu, Chukwuebuka Umeyor, Thaddeus Gugu, Calistus Nwakile, Chidalu Ikeotuonye. (2022, January), "Solidified Reverse Micellar Solution-(SRMS-) Based Microparticles for Enhanced Oral Bioavailability and Systemic Antifungal Efficacy of Miconazole Nitrate in Immunocompromised Mice", BioMed Research International, Vol. 2022, pp 9 pages |
| 7 | Tochukwu Chimdindu Okeke, Chukwuebuka Emmanuel Umeyor, Ifeanyi Thaddeus Nzekwe, Immaculeta Chikamnele Umeyor, Ngozi Maryann Nebolisa, Emmanuel Maduabuchi Uronnachi, Calistus Dozie Nwakile, Chizoba Austinline Ekweogu, Omoirri Moses Aziakpono, Anthony Amaechi Attama. (2022, April), "Formulation development of Azadirachta indica extract as nanosuppositories improves its intrarectal delivery for the treatment of malaria.", Recent Advances in Drug Delivery and Formulation, Vol. 16, (Issue 03), pp 217 - 233 |
| 8 | Emmanuel Uronnachi, Chidiogo Atuegwu, Chukwuebuka Umeyor, Calistus Nwakile, Josephat Obasi, Chidalu Ikeotuonye, Anthony Attama. (2022, May), "Formulation and evaluation of hair growth enhancing effects of oleogels made from Rosemary and Cedar wood oils", Scientific African, Vol. 16, pp e01223 |
| 9 | Dozie-Nwakile, O. C., Nwakile, C. D., Uchendu, I. K., Okoroiwu, H. U., & Onyemelukwe, N. F. (2022, July), "Prevalence, characterization, antimicrobial susceptibility pattern and factors associated with group B Streptococci (Streptococcus agalactiae) from clinical and non- clinical sources in South-East Nigeria", Journal of Biological Research |
| 10 | Emmanuel Maduabuchi Uronnachi, Anthony Attama, Franklin Kenechukwu, Chukwuebuka Umeyor,Thaddeus Gugu, Calistus Nwakile, Chidalu Ikeotuonye. (2022, January), "Solidified Reverse Micellar Solution- (SRMS-) Based Microparticles for Enhanced Oral Bioavailability and Systemic Antifungal Efficacy of Miconazole Nitrate in Immunocompromised Mice", BioMed Research International |
| 11 | Hilary Onwuchekwa, Emmanuel Uronnachi, Chukwuebuka Umeyor, Calistus Nwakile, Josephat Obasi, Ifeanyi Okeke, Charles Esimone. (2022, February), "Preparation, physicochemical characterization and in vivo evaluation of miconazole nitrate nanosponges for the treatment of systemic mycoses", GSC Biological and Pharmaceutical Sciences, Vol. 18, (Issue 2), pp 189-202 |
| 12 | Samson A Adejumo, Angus Nnamdi Oli, Ebere Innocent Okoye, Calistus Dozie Nwakile, Chioma Miracle Ojiako, Ugochukwu Moses Okezie, Ifeanyi Justin Okeke,. (2021, March), "Bio-surfactant Production Using Mutant Strains of Pseudomonas aeruginosa and Bacillus subtilis from Agro-industrial Wastes.", Advanced Pharmaceutical Bulletin, Vol. 11, (Issue 3), pp 543-556. |
| 13 | Calistus D Nwakile, Ogechukwu C Dozie-Nwakile, Ikenna K Uchendu, Vincent C Okore. (2021, May), "Shelf life of formulated herbal liquid dosage form of Picralima nitida seed extract for anti-hyperglycaemic indication", Tropical Journal of Natural Product Research, Vol. 5, (Issue 5), pp 932-937 |
| 14 | Dozie Nwakile C, Dozie-Nwakile OC, Okoye EI, Umeyor CE., Uronnachi EC, Uchend IK, Attama AA, Okore VC.. (2021, January), "Non-Absorbable Oral Gentamicin Sulphate: Biopharmaceutical and Dosage Form Evaluation.", Eur. Pharm. J., pp 1-8. |
| 15 | Chukwuebuka E. Umeyor, Amarachukwu U. Okonkwo, Ozioma D. Ejielo, Immaculeta C. Umeyor, Emmanuel M. Uronnachi, Calistus D. Nwakile, Ifeanyi J. Okeke, Anthony A. Attama. (2021, September), "Formulation design and preclinical evaluations of surface modified lipid nanoparticles-coupled gel encapsulating dihydroartemisinin for treatment of localized inflammation", Letters in Applied NanoBioScience, Vol. 11, (Issue 3), pp 3745-3769 |
| 16 | Azubuike Tobias Okolie , Chukwuebuka Emmanuel Umeyor, Calistus Dozie Nwakil, Ebere Innocent Okoye, Tochukwu Chimdindu Okeke, Emmanuel Uronnachi. (2021, September), "Formulation design and evaluation of the physicotechnical and hypoglycaemic properties of tablets containing Dioscorea dumetorum fraction in alloxanized diabetic rats", Journal of medicinal herbs, Vol. 12, (Issue 03), pp 49-59 |
| 17 | Gloria Ogochukwu Chinwuko, Ugochukwu Moses Okezie, Calistus Dozie Nwakile, Adekunle Babajide Rowaiye, Ifeanyi Justin Okeke, Angus Nnamdi Oli. (2021, June), "Preliminary study on the synergistic interaction of Garcinia kola and Vernonia amygdalina against Candida albicans", GSC Biological and Pharmaceutical Sciences,, Vol. 15, (Issue 03), pp 206–211 |
| 18 | Ogechukwu C Dozie-Nwakile, Calistus D Nwakile, Ikenna K Uchendu, Henshaw U Okoroiwu, Ngozi F Onyemelukwe. (2021, May), "Effects of Botanicals on Growth and Aflatoxin Production by Aspergillus flavus Infecting Maize", Tropical Journal of Natural Product Research, Vol. 5, (Issue 5), pp 943-951 |
| 19 | Emmanuel Uronnachi, Anthony Attama, Chukwuebuka Umeyor, Calistus Nwakile, Franklin Kenechukwu, Joy Reginald-Opara. (2020, January), "Solidified reverse micellar solution-based lipid microparticles of miconazole nitrate: formulation design, biopharmaceutical characterization, and dissolution studies.", Journal of Pharmaceutical Innovation., pp 1-15 |
| 20 | Dozie-Nwakile OC, Onyemelukwe NF, Nwakile CD, Okenwa CE, Okongwu U, Ukpai NU, Ilo AC. (2020, May), "Nutritional Sustainability for a Child towards Isolation of Aspergillus Species from Some Cereals and Legumes Sold in Enugu.", Acta Scientific Nutritional Health, Vol. 4, (Issue 5), pp 55-59. |
| 21 | Dozie-Nwakile OC, Nwakile CD, Onyemelukwe NF, Aladenika S, Uchenna AC, Ugwu EC.. (2020, March), "Antibacterial and Antifungal Effects of Carica papaya and Cucurbita specie Seed Extracts on Escherichia coli and Aspergillus flavus,", Journal of Drug Delivery and Therapeutics., Vol. 10, (Issue 3), pp 189-195 |
| 22 | Dozie-Nwakile OC, Nwakile CD, Uchendu IK, Okonkwo FC, Onyemelukwe NF. (2020, September), "Effects of kolaviron on pneumonia-like infection induced in albino wistar rats.", Antiinflamm Antiallergy Agents Med Chem. |
| 23 | Ezema CI, Amarachukwu CN, Esom EA, Dozie-Nwakile OC, Nwakile CD, Aladenika ST, Eze CU, Onyemelukwe NF, Okoye GC.. (2019, February), "Effect of long time Kolaviron administration on blood glucose level among apparently healthy sedentry albino Wistar rats.", International Journal of Herbs and Pharmacological Research IJHPR, Vol. 8, (Issue 2), pp 20-24 |
| 24 | P. Ndam, Ngozi Onyemelukwe, Calistus Dozie Nwakile, Uzoamaka Maduakor. (2018, February), "Antifungal properties of methanolic extracts of some medical plants in Enugu, south east Nigeria.y", African Journal of Clinical and Experimental Microbiolog, Vol. 19, (Issue 2), pp 141- 148. |
| 25 | Uronnachi Emmanuel Maduabuchi, Ude Ikechukwu Chris, Umeyor Chukwuebuka Emmanuel, Nwakile Calistus Dozie, Osonwa Uduma Eke (2017).. (2017, April), "Evaluating the potential of a novel co-processed excipient (stagua) as a binder in the production of vitamin C tablets.", British Journal of Pharmaceutical and Medical Research., Vol. 2, (Issue 4), pp 492-501. |
| 26 | Chukwuebuka Umeyor, Anthony Attama, Emmanuel Uronnachi, Franklin Kenechukwu, Calistus Nwakile, Ifeanyi Nzekwe, Eric Okoye, Charles Esimone. (2016, May), "Formulation design and in vitro physicochemical characterization of surface modified self-nanoemulsifying formulations (SNEFs) of gentamicin.", International Journal of Pharmaceutics, Vol. 497, pp 161–198 |
| 27 | Ikegbunam Moses Nkechukwu, Anagu Linda Onyeka, Nwakile Calistus D, A. Afunwa Ruth, Esimone Charles Okechukwu. (2014, November), "Antimicrobial Activity of Selected Medicinal Plants of South-Eastern Nigeria on Pseudomonas species Expressing Extended Spectrum Beta Lactamase (ESBL).", European Journal of Medicinal Plants, Vol. 4, (Issue 11), pp 1367-1377 |
| 28 | Nwagba CA, Ezugwu CO, Eze, CC, Anowi FC, Ezea SC, Nwakile CD. (2013, February), "Anti-ulcer Activity of Bombax Buonopozense P. Beauv. Aqueous leaf Extract (Fam: Bombacaceae).", J App Pharm Sci,, Vol. 3, (Issue 2), pp 139-142. |
| 29 | Eze CC, Anowi FC, Nwakile CD, Ugwu MC, Umeyor EC, Uronnachi EM, Nduka SO, Ugwuozor GPL, Ezea SC, Ezugwu CO.. (2013, December), "Evaluation of the anti-ulcer properties of the methanol extract of Prosopis africana taubert (Fam: Fabaceae) leaf.", International Journal of Pharmaceutical Research and Development., Vol. 4, (Issue 12), pp 001-006. |
| 30 | Chinedu Fredrick Anowi, Emezie AU, Calistus Nwakile, Ifanyi Alex Chukwu. (2013, April), "Preliminary Phytochemical Studies and Antimicrobial Activity of the Aqueous Extract of the Leaves of Dichapetalum madascariense, Poir, Family Dichapetalaceae.", Research J. Pharm. and Tech., Vol. 6, (Issue 4), pp 440-444 |
| 31 | Onochie ITO, Nwakile CD, Umeyor CE, Uronnachi EM, Osonwa UE, Attama AA, Esimone CO. (2013, December), "Formulation and Evaluation of Niosomes of Benzyl Penicillin.", J App Pharm Sci,, Vol. 3, (Issue 12), pp 066-071. |
| 32 | CO Esimone, AA Attama, UE Osonwa, CD Nwakile, FTO Onochie. (2012, March), "Formulation and evaluation of goat fat and shea butter based lipospheres of benzyl penicillin.", IJPSR, Vol. 3, (Issue 4), pp 1022-1027 |
| 33 | Uduma Eke Osonwa, Chukwuebuka Emmanuel Umeyor, Uduak Victor Okon, Emmanuel Maduabuchi Uronnachi, Calistus Dozie Nwakile. (2012, June), "Stability Studies on the Aqueous Extract of the Fresh Leaves of Combretum Micranthum G.Don Used as Antibacterial Agent", J. Chem. Chem. Eng., Vol. 6, pp 417-424 |
| 34 | Moses N Ikegbunam, Calistus D Nwakile, Malachy C Ugwu, Daniel L Ajaghaku and Charles O Esimone. (2012, May), "Sensitivity of Pseudomonas species expressing extended spectrum beta lactamase to different solvent fractions of milletia aboensis.", Journal of Natural Sciences Research, Vol. 2, (Issue 9), pp 82-87 |
| 35 | Chukwuebuka E Umeyor, Franklin C Kenechukwu, Emmanuel M Uronnachi, Uduma E Osonwa, Calistus D Nwakile .. (2012, March), "Solid Lipid Microparticles (SLMS): An Effective Lipid Based Technology for Controlled Drug Delivery.", Am. J. PharmTech Res., Vol. 2, (Issue 6), pp 1-18 |
| 36 | Calistus D Nwakile, Godswill C Onunkwo, Uduma E Osonwa, Chukwuemeka E Umeyor, Emmanuel M Uronnachi. Obinna C Emesih.. (2012, January), "Effects of Glycerine and Paraffin Additives on Tablet Properties of Riboflavin Prepared from Detarium microcarpium, Gelatine and Ethyl Cellulose.", Journal of Pharmacy Research., Vol. 5, (Issue 10), pp 5048-5051. |
| 37 | Calistus D Nwakile, Vincent C. Okore. (2012, December), "Pulp of Picralima nitida for hypoglycemic indication: micromeritic and stability assessment.", Journal of Pharmacy Research., Vol. 5, (Issue 12), pp 5253-5256 |
| 38 | Calistus Dozie Nwakile, Uduma Eke Osonwa, Ogechukwu Calista Okechi, Christian Chibuzor Opurum, Christopher Ezeh Nwanyanwu. (2011, June), "Microbial and Physicochemical qualities of selected Co-trimoxazole and Metronidazole formulations in South Eastern Nigerian", Journal of Advanced Pharmacy Education & Research, Vol. 2, pp 81-89 |
| 39 | Calistus Dozie Nwakile, Vincent C. Okore. (2011, March), "Picralima Nitida Seed Oil I: Hypoglycemic Activity", Journal of Advanced Pharmacy Education & Research, Vol. 2, pp 147-153 |
| 40 | Okore VC, Umeh ICJ, Nwakile CD. (2007, April), "Anti staphylicoccoal activity of Jatropha curcus latex in the presence of some Surfactants or human serum: implicantions for treatment of skin infections.", Bio-Research, Vol. 5, (Issue 2), pp 284-289 |
Academic Leadership Qualities
| Supervisions | |
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| 1 | "Evaluating the effect of polyvinlidyl- mannitol-lecithin composite on the release profile of oral furosemide, a BCS class IV drug" (2021). Completed Masters project by Ekweogu Austinline Chizoba |
| 2 | "Potentials ofGarcinia kola and Vernonia amygdalina ethanolic extract in the treatment of infections caused by Mycobacterium tuberculosis" (2023). Completed Masters project by Ezechukwu Ogonna Dorathy (201765E6006P) |
| 3 | "Gentamicin sulphate emulsion for systemic indication: formulation development and evaluation" (2023). Completed Masters project by Ewuzie Somtochukwu Richard (201965E6001FA) |
| 4 | "Formulation and physicotechnical characterization of tablets containing aqueous fraction from methanolic extract of Dioscorea dumentorum for the management of Diabetes Mellitus" (2021). Completed Masters project by Okolie Azubuike Tobias (201665E002F) |
| Grants | |
| 1 | Awardee: "Enhancement of service delivery in the University" (December, 2019 to December, 2019). Completed sponsored grant by Nnamdi Azikiwe University |
| 2 | Awardee: "PASMAT Biomaterials Workshop" (August, 2018 to August, 2018). Completed sponsored grant by Pan-African Materials Instutute |
| 3 | Awardee: "PASMAT Biomaterials Workshop" (November, 2015 to November, 2015). Completed sponsored grant by Pan-African Materials Instutute |
| 4 | Awardee: "1st Pan African Summer School in Nanomedicine" (November, 2012 to June, 2012). Completed sponsored grant by South African Department of Science and Technology |
| 5 | Awardee: "Nanotechnology and Biotechnology workshop" (November, 2012 to December, 2012). Completed sponsored grant by FUT-MINNA STEP B PROGRAM |
| Reviewerships | |
| 1 | Reviewer, "A Review on Nutritional Properties and Health Benefits of Finger Millet for Healthy Life" (July, 2023) |
| 2 | Reviewer, "Study on the effect s of methanol extract of A llium cepa (onions) on adriamycin - induced hepato - renal damage in experimental rat mode" (November, 2021) |
| 3 | Reviewer, "Isolation, Purification and Antimicrobial activity of Cannabinoids from Cannabis sativa flowers" (November, 2021) |
| Examinerships | |
| 1 | Examiner, "Higher degree examinations in the Department of Pharmaceutics, University of Nigeria Nsukka, Enugu State Nigeria for 2018/2019 session" (April, 2019). Completed External Exam |
| 2 | Examiner, "1. External examiner for undergraduate examinations for 2017/2018 session, Department of Pharmaceutical Microbiology and Biotechnology, University of Nigeria Nsukka, Enugu State Nigeria." (October, 2018 to October, 2018). Completed External Exam |
| Contributions to the University/Society | |
| 1 | Member, "Senate Ad hoc committee, nnamdi Azikiwe University Awka" (February, 2022 to November, 2022) |
| 2 | Assistant corps Commander (ACC), "Nigerian Region corps of Commissionaires" (June, 2017 to June, 2017) |
| 3 | SIWES coordinator, "Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University Awka, Anambra State" (October, 2014 to September, 2019) |
| 4 | Faculty Examination Officer, "Faculty of Pharmaceutical Sciemces, Nnamdi Azikiwe University Awka" (October, 2010 to September, 2011) |