Prof. Afamefuna Felix Onyegbule

Prof. Afamefuna Felix Onyegbule is a PROFESSOR in PHARMACEUTICAL AND MEDICINAL CHEMISTRY Department, Faculty Of Pharmaceutical Sciences in Nnamdi Azikiwe University

Prof. Afamefuna Felix Onyegbule

Personal Information

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Address:
Pharmaceutical And Medicinal Chemistry, Faculty Of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka.
Faculty/Unit:
FACULTY OF PHARMACEUTICAL SCIENCES
Department/Sub-Unit:
PHARMACEUTICAL AND MEDICINAL CHEMISTRY

Academic Qualifications

Degrees / Basic Certificates
1University Of Benin, Edo State. (Doctor of Philosophy, October, 2014)
June, 2007 to September, 2014
PhD Pharmaceutical Chemistry

Creative Output

Journal Articles
1Ebere Ifejirika Ezeonyi, Earnest Oghenesuvwe Erhirhie, Felix Ahamefule Onyegbule. (2024, April), "Toxicity study and ameliorative effects of the aqueous leaf extract of Lecanoidiscus cupanioides Planch (ex. Benth) on the stress-induced ulcer", International Journal of Plant Based Pharmaceuticals, Vol. 4, (Issue 1), pp 47-55
2Ogechukwu L. Chukwuemerie, Samuel J. Bunu, Ezinne S. Iloh, Chukwunonso C. Onwuzuluigbo, Felix A. Onyegbule, Festus B. C. Okoye. (2022, November), "Antimicrobial Properties and Characterization of Secondary Metabolites Obtained from Curvularia lunata, an Endophyte of Azadirachta indica", J. Drug Deliv. Ther, Vol. 12, (Issue 6), pp 110-119
3Ebere C Ifejirika, Eze E Ajaegbu, Chioma I Ibe, Felix A Onyegbule, Obidike C Ezugwu. (2022, March), "Antioxidant and antimicrobial evaluation of the methanol leaf extract and fractions of Dacryodes Klaineana Pierre (Burseraceae)", Bulletin of the Chemical Society of Ethiopia, Vol. 36, (Issue 1), pp 85-94
4Amara A Ajaghaku, Daniel L Ajaghaku, Felix A Onyegbule, Festus Basden C Okoye. (2021, August), "Estrogenic and safety evaluation of root extract of Millettia aboensis as a potential plant derived alternative for hormone replacement therapy", South African Journal of Botany, Vol. 140, pp 123-134
5Stella O. Bruce, Felix A. Onyegbule, Christopher O. Ezugwu, Ifeoma D. Nweke, Chioma R. Ezenwelu, Felix I. Nwafor. (2021, April), "Chemical Composition, Hepatoprotective and Antioxidant Activity of the Crude Extract and Fractions of the Leaves of Fadogia Cienkowskii Schweinf (Rubiaceae)", Tropical Journal of Natural Product Research, Vol. 5, (Issue 4), pp 720-731
6Stella O Bruce, Felix A Onyegbule, Ogechi O Anyanwu, Chioma R Ezenwelu, Christopher O Ezugwu. (2021, November), "Bioactive constituents, hepatoprotective and antioxidant activity of the Sub-fractions of Fadogia cienkowskii leaves Schweinf (Rubiaceae)", Journal of Scientific and Innovative Research, Vol. 10, (Issue 4), pp 81-88
7Felix A Onyegbule, Chidinma J Ezenwa, Stella O Bruce, Umeokoli Blessing O.. (2020, May), "Standardization, Chemical Composition and Antipyretic Evaluation of the Methanol Leaf Extract and Fractions of Chrysophyllum albidum (Sapotaceae)", Tropical Journal of Natural Product Research, Vol. 4, (Issue 6), pp 216-222
8Amara A. Ajaghaku, Daniel L. Ajaghaku, Felix A. Onyegbule, Festus Basden . Okoye. (2020, December), "Suppression of IL-6 mediated NF � �B signaling pathway as possible osteoprotective mechanism of Millettia aboensis", Phytomedicine Plus, Vol. 1, (Issue 1), pp 1-11
9Ifeanyi P. Onyeka, Sunday P. Bako, Mohammed M. Suleiman, Felix Afamefula Onyegbule, Ugonna C. Morikwe, Cyril Onyeka Ogbue. (2020, November), "Antiulcer Effects of Methanol Extract of Euphorbia hirta and Honey Combination in Rats", BioMed Research International, Vol. 827504, pp 1-8
10SO Bruce, FA Onyegbule, CO Ezugwu. (2019, October), "Pharmacognostic, physicochemical and phytochemical evaluation of the leaves of Fadogia cienkowski Schweinf (Rubiaceae)", Journal of Pharmacognosy and Phytotherapy, Vol. 11, (Issue 3), pp 52-60
11Onyegbule F. A., Bruce S. O., Onyekwe O. N., Onyealisi O. L. and Okoye P. C. (2019, June), "Evaluation of the in vivo antiplasmodial activity of ethanol leaf extract and fractions of Jatropha gossypifolia in Plasmodium berghei infected mice", Journal of Medicinal Plants Research, Vol. 13, (Issue 11), pp 269-279
12Blessing O. Umeokolia,b, Felix A. Onyegbuleb, Festus B.C. Okoyeb, Hao Wanga, Rainer Kalscheuera, Werner E.G. Müllerc, Rudolf Hartmannd, Zhen Liua,⁎, Peter Prokscha. (2017, August), "New amide and dioxopiperazine derivatives from leaves of Breynia nivosa", Fitoterapia, Vol. 122, pp 16-19
13Eguji Vincent Igwebuike1, Onyegbule Felix Ahamefule2* and Ezugwu Christopher Obododike3. (2017, June), "Standardization and evaluation of anticonvulsant activities of leaf extract and fractions of Waltheria indica", Asian Pac. J. Health Sci., Vol. 4, (Issue 2), pp :61-75
14Onyegbule F.A., Umeokoli B.O., Anyama K.K., Anasi H., Eze P.M., Okafor U.G. (2017, September), "QUALITY ASSESSMENT OF SIX LIQUID HERBAL PREPARATIONS MARKETED IN ANAMBRA STATE, NIGERIA", African Journal of Pharmaceutical Research & Development, Vol. 9, (Issue 1), pp 96- 101
15Bruce S.O., Onyegbule F.A1, and Ihekwereme C.P.. (2016, December), "EVALUATION OF THE HEPATO-PROTECTIVE AND ANTI-BACTERIAL ACTIVITIES OF ETHANOL EXTRACT OF Picralima nitida SEED AND POD", Journal of Phytomedicine and Therapeutic, Vol. 15, (Issue 2), pp 1-21
16Ogechukwu Blessing Umeokoli, Chika Abba, Peter Eze, Daniel Ajaghaku, Felix Ahamefule Onyegbule. (2016, October), "Antimicrobial, anti-inflammatory, and chemical evaluation of Buchholzia coriacea seed (Wonderful Kola)", American Journal of Life Sciences, Vol. 4, (Issue 5), pp 106-112
17Festus BC Okoye, Wilfred O Obonga, Felix A Onyegbule, Okechukwu O Ndu, Chibueze P Ihekwereme. (2014, June), "Chemical composition and anti-inflammatory activity of essential oils from the leaves of Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae )", Society of Pharmaceutical Sciences and Research, India, Vol. 5, (Issue 6), pp 2174-2180
18Felix A Onyegbule, Innocent O Ilouno, Peter M Eze, Chika C Abba, Victor U Chigozie. (2014, December), "Evaluation of the analgesic, anti-inflammatory and antimicrobial activities of leaf extracts of Breynia nivosa", Chemical Science Review and Letters, Vol. 3, (Issue 12), pp 1126-1134
19FA Onyegbule, EC Onyegbule, BO Umeokoli. (2013, August), "Effects of oral administration of ethanolic extract of Vernonia amygdalina on enzymes associated with liver function in experimental rabbits", Planta Medica, Vol. 79, (Issue 13), pp PB38
20BO Umeokoli, FA Onyegbule, TH Gugu, SO Igboeme. (2013, August), "Evaluation of the erythropoietic and anti-sickling properties of Ficus capensis leaf extract in the treatment of anaemia", Planta Medica, Vol. 79, (Issue 13), pp PE29