Prof. Chibueze Peter Ihekwereme is a PROFESSOR in PHARMACOLOGY AND TOXICOLOGY Department, Faculty Of Pharmaceutical Sciences in Nnamdi Azikiwe University
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Address: | Pharmacology And Toxicology, Faculty Of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka. |
Faculty/Unit: | FACULTY OF PHARMACEUTICAL SCIENCES |
Department/Sub-Unit: | PHARMACOLOGY AND TOXICOLOGY |
| Degrees / Basic Certificates | |
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| 1 | Nnamdi Azikiwe University, Awka, Nigeria. (Doctor of Philosophy, February, 2014) June, 2009 to February, 2014 PhD Pharmacology & Toxicology |
| 2 | University Of Nigeria, Nsukka. (Master Degree, January, 2002) January, 1999 to January, 2002 Master Of Pharmacy Pharmacology & Toxicology |
| 3 | University Of Nigeria, Nsukka. (Bachelor Degree, December, 1998) October, 1991 to December, 1998 Bachelor Of Pharmacy Pharmacy |
| Journal Articles | |
|---|---|
| 1 | Moses Ikegbunam, Nwokike Uchechukwu, Harrison Abone, Ani Ezinne Grace, Mercy Ezeunala, Nnanna Joy, Nzeukwu Chibumma Immaculata, Joy Ogugua Igwe, Obiageli Okeke, Frances Nworji, Peter Ihekwereme. (2026, February), "No G6PD A-(G202A) variant detected among Plasmodium falciparum-positive patients in Awka, Southeast Nigeria: a hospital-based study", Malaria World Journal, Vol. 17, (Issue 4) |
| 2 | Omo Eric Irinmwinuwa, Chibueze P. Ihekwereme, Udoudo Isaac Etim, Ugenyi Lovelyn Chinyeaka, Nicholas Clement Nwachinemere, Echem Chukwubuikem Agada, Chukwuka Benjamin Uzodinma. (2026, January), "Antibacterial activity of ethanol extract of Monodora myristica seed", American Journal of Plant Sciences, Vol. 17, (Issue 1) |
| 3 | Philip A. Obarisiagbon, Chibueze P. Ihekwereme. (2025, December), "Antiplasmodial, toxicological and smooth muscles effect of acetone and ethyl acetate fractions of the fruit pulp of Chrysophyllum albidium", Nigerian Journal of Pharmaceutical Research, Vol. 21, (Issue 1) |
| 4 | Daniel Lotanna Ajaghaku, Chibueze Peter Ihekwereme, Paul Chinwuba. (2025, August), "Effect of Supplementation with Phenol Rich Fraction of Musanga cecropioides on Malaria and Primaquine Induced Oxidative Stress in Mice", Asian Journal of Biology, Vol. 21, (Issue 8), pp 70-87 |
| 5 | Mba Ogbonnaya, Chibueze P. Ihekwereme, Uchechukwu H. Orji, Aziakpono M. Omoirri. (2024, September), "Antiplasmodial activities of n-hexane and water fractions of Dennettia tripetala leaf extract in Wistar rats", World Journal of Biology Pharmacy and Health Sciences, Vol. 19, (Issue 3), pp 595–602 |
| 6 | Peter Chibueze Ihekwereme, Daniel Ikechukwu Oraekei, Rose Ngozi Asomugha, Harrison Odera Abone, Matthew Ikechukwu Ezugwu, Marcellus Ejike Nnamani. (2024, August), "Anti-breast cancer activities of Zingiber officinale and Allium sativum ethanol extracts in 7, 12-dimethylbenz [a] anthracene induced female Wistar rats", GSC Biological and Pharmaceutical Sciences, Vol. 29, (Issue 1), pp 224–232 |
| 7 | Daniel Ikechukwu Oraekei, Peter Chibueze Ihekwereme, Rose Ngozi Asomugha, Harrison Odera Abone, Matthew Ikechukwu Ezugwu, Nnamdi Markben Adione. (2024, August), "Potentials of Zingiber officinale and Allium sativum ethanol extracts to inhibit oxidative stress and inflammation resulting from cancer inducement with 7,12- dimethylbenz[a]anthracene", World Journal of Biology Pharmacy and Health Sciences, Vol. 19, (Issue 2), pp 340–350 |
| 8 | Chima Ernest Orji, Okwelogu I Somadina, Chibueze P. Ihekwereme, Victoria N. Olli, Jude Nnaemeka Okoyeh. (2024, June), "Off-label use of tramadol combined with Lacasera® soft drink: A sub-acute toxicological study using Wistar rats to evaluate the effects of combination on human basic haematological parameters and weight changes", Research Journal of Pharmacy and Technology, Vol. 17, (Issue 6), pp 2761- 2768 |
| 9 | Daniel Ikechukwu Oraekei, Peter Chibueze Ihekwereme, Chukwuka Benjamin Uzodinma, Marcellus Ejike Nnamani. (2024, May), "Modulation of female reproductive hormones by Zingiber officinale and Allium sativum ethanol extracts administered singly and in combinations in female Wistar rats", Magna Scientia Advanced Biology and Pharmacy, Vol. 12, (Issue 1), pp 024–031 |
| 10 | Daniel Ikechukwu Oraekei, Peter Chibueze Ihekwereme, Chukwuka Benjamin Uzodinma, Onyeka Chinwuba Obidiegwu, Marcellus Ejike Nnamani. (2024, January), "Elucidation of the effects of combined administration of Zingiber officinale and Allium sativum ethanol extracts on lipid profile by means of female Wister rat models", World Journal of Biology Pharmacy and Health Sciences,, Vol. 17, (Issue 1), pp 220–227 |
| 11 | Daniel Ikechukwu Oraekei, Peter Chibueze Ihekwereme, Chukwuka Benjamin Uzodinma, Onyeka Chinwuba Obidiegwu, Marcellus Ejike Nnamani, Nnamdi Markben Adione. (2024, January), "Evaluation of the protective effects of co-administered Zingiber officinale and Allium sativum ethanol extracts on hepatic and renal functions using female Wister rat models", GSC Biological and Pharmaceutical Sciences, Vol. 26, (Issue 1), pp 268 - 274 |
| 12 | Akachukwu, A., Ikegbunam, M., Enyi, E., Onochie-Igbinedion, T.O.I., Abone, H., Ezeagwuna, D., Nnanna, J., Ihekwereme, C. and Nworu, C. (2023). (2023, June), "Evaluation of Antiplasmodial Effect of Methanol Leaf Extract and Fractions of Eucalyptus camadulensis (Denhn) in Albino Wistar Mice. American Journal of Plant Sciences, 14, 662-676. doi: 10.4236/ajps.2023.146045.", American Journal of Plant Sciences, Vol. 14, (Issue 6) |
| 13 | Orji CE, Uzochukwu IC, Ihekwereme CP, Okoyeh JN. (2021, February), "Comparative Analysis Of Lead In Rats Organs Using FAAS And XRF: Insight On Suitable Equipment In Forensic Investigation Of Heavy Metal Poisoning In Humans", Journal of Chemical, Biological and Physical Sciences |
| 14 | Onochie AU, Oli AH, Oli AN, Ezeigwe OC, Nwaka AC, Okani CO, Okam PC, Ihekwereme CP, Okoyeh JN. (2020, October), "The Pharmacobiochemical Effects Of Ethanol Extract Of Justicia Secunda Vahl Leaves In Rattus Norvegicus", Journal of Experimental Pharmacology |
| 15 | Ihekwereme CP, Agafuchukwu P, Erhirhie EO. (2020, June), "Artesunate (ART) Antagonizes Antiplasmodial Activity Of Vernonia Amygdalina Methanol Leaf Extract In Murine Model Of Malaria", American Journal of Physiology, Biochemistry And Pharmacology |
| 16 | Orji CE, Okpoko CK, Agbata CA, Okoyeh JN, Okeke AC, Ihekwereme CP. (2020, June), "Evaluation Of The Effect Of Luteolin On The Hepatic And Hematopoietic Systems In Albino Rats", Journal of Clinical Toxicology |
| 17 | Nwobodo DC, Ihekwereme CP, Ikem CJ, Okoye FBC. (2020, February), "The Anti-pseudomonal Potentials Of Metabolites From Some Endophytic Fungi Isolated From Garcinia Kola Leaves", Novel Research in Microbiology Journal |
| 18 | Ihekwereme CP, Bruce SO, Orji CE, Ibe CI, Iloh ES. (2020, April), "Aqueous Extracts Of Ocimum Gratissimum And Anacardium Occidentale Synergises In Anti-diarrhoeal Property", International Journal of Modern Pharmaceutical Research, Vol. 4, (Issue 4), pp 6 - 11 |
| 19 | Odenigbo AE, Akah PA, Ilodigwe EE, Ajaghaku DL, Erhirhie EO, Ogbonnaya M, Ihekwereme CP. (2020, May), "Preliminary Evaluation Of The Antidiarrheal Effects Of Ethanol Leaf Extract And Fractions Of Rauwolfia Vomitoria Afzel. (Apocynaceae)", International Journal of Pharmacology, Phytochemistry and Ethnomedicine, Vol. 15, pp 11 - 21 |
| 20 | Oli AN, Emeruwa AP, Ekwunife OI, Okoye EL, Anyaoku CS, Ibeanu GC, Obi E, Ihekwereme CP, Obaji M. (2019, September), "Pleurotus Ostreatus Extract Enhances The Phagocytic Actions Of Neutrophils Against Streptococcus Pneumonia", Annals of Medical and Health Sciences Research, Vol. 7, (Issue 2), pp 499- 508 |
| 21 | Erhirhie OE, Ilodigwe EE, Ihekwereme CP. (2018, July), "Ficus Sycomorus L (Moraceae): A Review On Its Phytopharmacology And Toxicity Profile", Discovery Phytomedicine, Vol. 5, (Issue 4), pp 64-71 |
| 22 | Osonwa UE, Okechukwu SA, Ihekwereme CP, Chukwu KI, Eluu SC, Azevedo RB. (2018, March), "Formulation And Evaluation Of Therapeutic Potential Of Nanoemulsion Of A Blend Of Antimicrobial Oils", Trop J Nat Prod Res, Vol. 2, (Issue 2), pp 67-73 |
| 23 | Ihekwereme CP, Melidem CO, Maduka IC, Okoyeh JN. (2018, February), "In Vivo Antiplasmodial And Toxicological Effects Of Extracts Of Fruit Pulp Of Chrysophyllum Albidium G. Don (Sapotaceae)", Trop J Nat Prod Res, Vol. 2, (Issue 3), pp 126-131 |
| 24 | Chibueze Peter Ihekwereme, Chukwusom Maureen Aniezue, Earnest O Erhirhie, Uche Gabriel Okafor. (2015, January), "Preliminary Evaluation of the Anti-Emetic Activity of Crude Methanol Extract and Fractions of Ocimum gratissimum", Journal of Developing Drugs, Vol. 5, (Issue 1), pp 149 |
| 25 | Chibueze Peter Ihekwereme, Charles Okechukwu Esimone, Edward Chieke Nwanegbo. (2014, February), "Hemozoin Inhibition and Control of Clinical Malaria", Advances in Pharmacological Sciences, Article ID 984150 |
| 26 | Miracle Oluebubechukwu Obiagwu, Chibueze Peter Ihekwereme, Daniel Lotanna Ajaghaku, Festus Basden Chinedu Okoye. (2014, January), "The Useful Medicinal Properties of the Root-Bark Extract of Alstonia boonei (Apocynaceae) May Be Connected to Antioxidant Activity", ISRN Pharmacology, Vol. 2014, Article ID 741478 |
| 27 | Nduka Sunday Odunke, Okonta Eleje, Abba Chika Christiana, Ihekwereme Chibueze Peter, Ekwedigwe Uchenna. (2014, April), "Herb drug interaction Effect of manix® on pharmacokinetic parameters of pefloxacin using rat model", Asian Pacific Journal of Tropical Biomedicine, Vol. 4, (Issue 1), pp S413-S416 |
| 28 | Chibueze Ihekwereme, Charles Esimone, Di Shao, Remigius U. Agu. (2014, June), "Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity", Pharmaceutics (Special issue: Respiratory and Nasal Drug Delivery), Vol. 6, pp 268-280 |
| 29 | E.E. Ilodigwe, E.N. Igbokwe, D.L. Ajaghaku, C.P. Ihekwereme. (2013, January), "Aphrodisiac activity of ethanol root extract and fractions of Landolphia dulcis (sabine) pichon", International Journal of Pharmaceutical Sciences and Research, Vol. 4, (Issue 2), pp 813-818 |
| 30 | Charles O. Esimone, Chibueze P. Ihekwereme, Ifeanyi E. Okoye, Michael U. Adikwu. (2013, July), "Urinary Elimination of Ofloxacin in Humans is Reduced by TEA and Kola nitida Seed.", African Journal of Pharmaceutical Sciences and Pharmacy, Vol. 4, (Issue 1), pp 70-82 |
| 31 | Mohammad Mustafa, Mustafa El-Abadelah, Mohammad Mubarak, Ihekwereme Chibueze, Di Shao, Remigius Agu. (2011, October), "Synthesis and Fluorogenic Properties of Some 1-(Coumarin-7-yl)-4,5-dihydro-1,2,4- triazin-6(1H)-ones. I", International Journal of Chemistry, Vol. 3, (Issue 4) |
| Supervisions | |
|---|---|
| 1 | "Evaluation of acute and subchronic toxicities of a Nigerian polyherbal formulation" (2016). Completed Masters project by EBUNU, Gift Ishioma (Reg No: MSc./2013/65F6001F) |
| 2 | "The antidiarrhoeal activity of the methanol extract and fractions of the leaves of Dialiumguineense (Willd)" (2017). Completed Masters project by ADIBE, Uchenna Chisom (Reg No: MSc./2013/65F6007F) |
| 3 | "Evaluation of hepato-protective and antibacterial activities of ethanol extract and fractions of Picralima nitida seed and pod." (2016). Completed Masters project by BRUCE, Stella Omokhefe (Reg No: MSc./2014/65A007P) |
| 4 | "Pharmacodynamics of a blend of Zingiber officinale and Allium sativum against breast cancer in 7,12-dimethylbenz[a]. anthracene induced Rattus norvegicus" (2025). Completed Doctorate project by ORAEKEI, Daniel Ikechukwu (Reg. No: 202065F7004P) |
| 5 | "Analgesic, antipyretic and anti-inflammatory activity of ethanol root extract and fractions of Ficus capensis in rat" (2025). Completed Masters project by EMENEKA, Esther Ekene (Reg No: 201765F6001) |
| 6 | "Sub-acute Study on Administration of Graded Doses of Tramadol Dissolved in Lacasera Soft Drink: Evaluation of organs & Physiological Effects on Wistar Rats" (2024). Completed Masters project by ORJI, Earnest Chima (Reg. No: 201665f002F) |
| 7 | "Isolation and screening of secondary metabolites of endophytic fungi fromCola nitidaand Garcinia kola for their biological properties" (2019). Completed Masters project by NWOBODO, David Chinemerem (Reg No: MSc./2014/65C6001F) |
| 8 | "Effect of polyherbal antimalarial Super7 on female reproductive system using rat model" (2020). Completed Masters project by ORAEKEI, Daniel Ikechukwu (Reg. No: 201565F001P) |
| Grants | |
| 1 | Awardee: "Canadian Commonwealth Scholarship Program" (January, 2011 to July, 2011). Completed sponsored grant by Foreign Affairs & International Trade Canada |
| 2 | Awardee: "Congratulations ‐ Selection as Candidate for Training – PRD College" (January, 2010 to March, 2013). Completed sponsored grant by Poverty Related Disease (PRD) College |
| 3 | Awardee: "Academic Staff Development and Training Grant, Educational Trust Fund 2008 intervention" (October, 2009 to September, 2011). Completed sponsored grant by TETFUND (Formerly ETF) |
| Examinerships | |
| 1 | Chief Examiner, "MBBS II viva (oral) examination" (March, 2021 to March, 2021). Completed External Exam |
| 2 | Chief Examiner, "MBBS II viva (oral) re sit examination" (March, 2020 to March, 2020). Completed External Exam |
| 3 | Chief Examiner, "MBBS II viva (oral) examination" (December, 2019 to December, 2019). Completed External Exam |
| Accreditation Panel Memberships | |
| 1 | Member, "NUC Ad-hoc Accreditation Panel" (November, 2025) |