Prof. Onyenmechi Johnson Afonne
Prof. Onyenmechi Johnson Afonne is a PROFESSOR in PHARMACOLOGY AND THERAPEUTICS Department, Faculty Of Basic Clinical Sciences in Nnamdi Azikiwe University
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Personal Information
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Phone: | |
Address: | Pharmacology And Therapeutics, Faculty Of Basic Clinical Sciences, Nnamdi Azikiwe University, Awka. |
Faculty/Unit: | FACULTY OF BASIC CLINICAL SCIENCES |
Department/Sub-Unit: | PHARMACOLOGY AND THERAPEUTICS |
Social Profiles
Interest Areas
Academic Qualifications
| Degrees / Basic Certificates | |
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| 1 | Abia State University, Uturu, Abia State, Nigeria. (Doctor of Philosophy, March, 2007) October, 2002 to March, 2007 PhD Pharmacology & Toxicology |
| 2 | Nnamdi Azikiwe University, Awka, Nigeria. (Master Degree, December, 1998) October, 1997 to December, 1998 M.Sc. Pharmacology & Toxicology |
Relevant/Working Experience
| 1 | Dean, School of Postgraduate Studies, PAMO University of Medical Sciences, Port Harcourt, Rivers State September, 2025 to August, 2026 |
| 2 | Associate Provost, College of Postgraduate Studies, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria June, 2021 to Present |
| 3 | Subdean Postgraduate, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria October, 2015 to May, 2021 |
| 4 | Professor, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria May, 1999 to Present |
Creative Output
| Book Chapters | |
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| 1 | Afonne OJ, Ifediba EC. (2022, November) Natural Does Not Mean Safe IntechOpen |
| Journal Articles | |
| 1 | PE Osagie, OJ. Afonne, EC. Ifediba. (2026, May), "Assessment of the Influence of Cooking Methods on Antibiotics Residues in Chicken Meat", IPS Journal of Nutrition and Food Science, Vol. 6, (Issue 2), pp 841-848 |
| 2 | O Okorie, GC Akuodor, CE Ifediba, CC Ofor, OJ Afonne. (2024, May), "In rodents, methanol extract from Ritchiea capparoides leaf has analgesic, anti-inflammatory, and antipyretic properties", Asian Journal of Research in Medical and Pharmaceutical Sciences, Vol. 13, (Issue 2), pp 21-31 |
| 3 | CC Okoro, EC Ifediba, OJ Afonne. (2024, January), "Evaluation of in utero developmental toxicity of metformin hydrochloride in male albino rats", Drug Discovery, Vol. 18, (Issue 41) |
| 4 | UU Ezeani, OJ Afonne, MC Ezeani. (2024, February), "Humoral and cellular immune regulation in albino rat exposed to glyphosate and aluminum phosphide", Asia Pacific Journal of Medical Toxicology, Vol. 13, (Issue 4), pp 145-150 |
| 5 | NN Ezeama, N Okunna, OJ Afonne. (2023, November), "Assessment of vitamin A levels in breast milk and serum of lactating mothers in Southeast Nigeria", North African Journal of Food and Nutrition Research, Vol. 7, (Issue 16), pp 120-129 |
| 6 | Onyena AP, Nkwoji JA, Chukwu LO, Ifediba EC, Afonne OJ, Amachree D. (2023, August), "Metal pollution and ecological risk in water from Chanomi Creek, Warri, Niger Delta, Nigeria", Journal of Chemical Health Risks, Vol. 13, (Issue 4), pp 789-802 |
| 7 | Ezeama NN, Okunna N, Afonne OJ. (2023, August), "Dietary intake and status of selenium in breast milk and serum of lactating mothers in Awka, South East Nigeria", Nutrition and Health, Vol. 31, (Issue 2) |
| 8 | EC Ifediba, OJ Afonne. (2023, May), "Thermally degraded palm kernel oil increased serum 4- hydroxynonenal protein adduct formation and hepatotoxic indications in Wistar rats: vitamin C intervention", Toxicology Advances, Vol. 5, (Issue 1), pp 1 |
| 9 | Irinmwinuwa OE, Ifediba EC, Oyindamola J, Afonne OJ. (2023, April), "Haemopoietic actions of Justicia secunda leaf extracts in mice", Faculty of Medicine Universitas Padjadjaran, Vol. 10, (Issue 2), pp 65-74 |
| 10 | Afonne OJ, Chukwuka JU, Ifediba EC, Obi E. (2022, August), "Pollution indices of heavy metal contaminants in typical agrarian soil samples in Ihiala, South-East Nigeria", Health and Environment, Vol. 3, (Issue 1), pp 176-185 |
| 11 | Ezeani UU, Afonne OJ, Ezeani MC, Ehigiator BE. (2022, June), "Determination of pesticide residue levels in some common food crops: The suitability for human consumption", Journal of Toxicology and Environmental Health Sciences, Vol. 14, (Issue 1), pp 10-19 |
| 12 | Afonne OJ, Ifediba EC, Afonne AJ. (2022, September), "Sleep deprivation: A toxicogenic drive for neurodegenerative diseases and public health issue", Advances in Health and Behaviour, Vol. 5, (Issue 1), pp 233-241 |
| 13 | Irinmwinuwa EO, Afonne OJ,. (2022, August), "Investigation into the effect of ethanol leaf extract and fractions of Justicia Secunda on platelets and WBC counts in mice", Magna Scientia Advanced Research and Reviews, Vol. 6, (Issue 1), pp 001-007 |
| 14 | Afonne OJ, Ifediba EC. (2020, August), "Heavy metals risks in plant foods – need to step up precautionary measures", Current Opinion in Toxicology, Vol. 22, pp 1-6 |
| 15 | Afonne OJ, Chukwuka JU, Ifediba EC. (2020, July), "Evaluation of drinking water quality using heavy metal pollution indexing models in an agrarian, non-industrialised area of South-East Nigeria", Journal of Environmental Science and Health, Part A, Vol. 55, (Issue 12), pp 1406-1414 |
| 16 | Afonne OJ, Ehigiator EB, Okafor UU. (2017, May), "Health risk potentials of some metals via consumption of some food crops at Iruekpen, Southern Nigeria", Toxicology International, Vol. 24, (Issue 2), pp 140-149 |
| 17 | Ezeanosike OB, Afonne OJ. (2017, September), "Prognostic significance of micro RNA 150 marker in BCR-ABL positive chronic myeloid leukaemia patients on imatinib mesylate", International Journal of Contemporary Pediatrics, Vol. 4, (Issue 5), pp 1557-1561 |
| 18 | Obi E, Okafor C, Igwebe A, Ebenebe J, Afonne OJ, Ifediata F, Orisakwe OE, Nriagu JO, Basu N. (2015, January), "Elevated prenatal methylmercury exposure in Nigeria: evidence from maternal and cord blood", Chemosphere, Vol. 119, pp 485-489 |
| 19 | Obi E, Okafor C, Igwebe A, Ebenebe J, Afonne OJ, Ifediata F, Orisakwe OE, Nriagu JO, Basu N. (2015, January), "Elevated prenatal methylmercury exposure in Nigeria: Evidence from maternal and cord blood", Chemosphere, Vol. 19, pp 485-489 |
| 20 | Obi E, Orisakwe OE, Okafor C, Igwegbe A, Ebenebe J, Afonne OJ, Ifediata F, Nils B, Nriagu J. (2014, September), "Towards prenatal biomonitoring in eastern Nigeria: assessing lead levels and anthropometric parameters of newborns", Journal of UOEH, Vol. 36, (Issue 3), pp 159-170 |
| 21 | TIN Ezejiofor, CI Duru, AE Asagbra, AN Ezejiofor, OE Orisakwe, JO Afonne, E Obi. (2012, May), "Waste to wealth: Production of oxytetracycline using Streptomyces species from household kitchen wastes of agricultural produce", African Journal of Biotechnology, Vol. 11, (Issue 43), pp 10115-10124 |
| 22 | . Orisakwe OE, Igwilo IO, Afonne OJ, Maduabuchi UJ-M, Obi E, Nduka JC. (2006, September), "Heavy metal hazards of sachet water in Nigeria", Archives of Environmental & Occupational Health, Vol. 61, (Issue 5), pp 209-213 |
| 23 | OE Orisakwe, DD Akumka, AA Njan, OJ Afonne, OO Okechi. (2005, April), "Hepatotoxic and haematological effects of Nigerian Bonny light crude oil in male albino rats", Toxicological & Environmental Chemistry, Vol. 87, (Issue 2), pp 215-221 |
| 24 | Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. (2004, March), "Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats", Reproductive Toxicology, Vol. 18, (Issue 2), pp 295-298 |
| 25 | Orisakwe OE, Akumka DD, Njan, Afonne OJ. (2004, May), "Testicular toxicity of Nigerian bonny light crude oil in male albino rats", Reproductive Toxicology, Vol. 18, (Issue 3), pp 439-442 |
| 26 | OE Orisakwe, R Asomugha, OJ Afonne, CN Anisi, E Obi, CE Dioka. (2004, April), "Impact of effluents from car battery manufacturing plant on water, soil and food qualities in Nnewi, Nigeria", Archives of Environmental Health: An International Journal, Vol. 59, (Issue 1), pp 31-36 |
| 27 | Orisakwe OE, Njan AA, Afonne OJ, Akumka DD, Orish VN, Udemezue OO. (2004, September), "Investigation into the nephrotoxicity of Nigerian bonny light crude oil in albino rats", International Journal of Environmental Research and Public Health, Vol. 1, (Issue 2), pp 106-110 |
| 28 | Orisakwe OE, Afonne OJ, Chude MA, Obi E, Dioka CE. (2003, August), "Sub-chronic toxicity studies of the aqueous extract of Boerhavia diffusa leaves", Journal of Health Science, Vol. 49, (Issue 6), pp 444-447 |
| 29 | Dioka C, Orisakwe OE, Afonne OJ, Agbasi PU, Akumka DD, Okonkwo CJ, Ilondu N. (2002, June), "Investigation into the Haematologic and Hepatotoxic Effects of Rinbacin in Rats", Journal of Health Science, Vol. 48, (Issue 5), pp 393-398 |
| 30 | OJ Afonne, OE Orisakwe, CE Dioka, E Obi, T Ezejiofor, L Asomugha, U Ukoha. (2002, April), "Effects of rinbacin extract on rat kidney", Biological and Pharmaceutical Bulletin, Vol. 25, (Issue 8), pp 1022-1025 |
| 31 | Afonne OJ, Orisakwe OE, Obi E, Dioka CE, Ndubuka GI. (2002, April), "Nephrotoxic actions of low-dose mercury in mice: protection by zinc", Archives of Environmental Health: An International Journal, Vol. 57, (Issue 2), pp 98-102 |
| 32 | Afonne OJ, Orisakwe OE, Ekanem IA, Akumka DD. (2002, September), "Zinc protects chromium-induced testicular injury in mice", Indian Journal of Pharmacology, Vol. 34, (Issue 1), pp 26-31 |
| 33 | OJ Afonne, OE Orisakwe, SI Ofoefule, S Tsalha, E Obi, NA Ilondu, O Okorie. (2002, May), "Saline cathartics and adsorptive capacity of activated charcoal for doxycycline", Acta Poloniae Pharmaceutica - Drug Research, Vol. 59, (Issue 3), pp 177-180 |
| 34 | MA Chude, OE Orisakwe, OJ Afonne, KS Gamaniel, OH Vongtau, E Obi. (2001, May), "Hypoglycaemic effect of the aqueous extract of Boerhavia diffusa leaves", Indian Journal of Pharmacology, Vol. 33, (Issue 3), pp 215-216 |
| 35 | Orisakwe OE, Afonne OJ, Nwobodo E, Asomugha L, Dioka CE. (2001, March), "Low-dose mercury induces testicular damage protected by zinc in mice", European Journal of Obstetrics & Gynecology and Reproductive Biology, Vol. 95, (Issue 1), pp 92-96 |
| 36 | Orisakwe OE, Afonne OJ, Agbasi PU, Ilondu NA, Ofoefule SI, Obi E. (2001, December), "Adsorptive capacity of activated charcoal for rifampicin with and without sodium chloride and sodium citrate", Biological and Pharmaceutical Bulletin, Vol. 24, (Issue 6), pp 724-726 |
| 37 | Orisakwe OE, Asomugha R, Obi E, Afonne OJ, Dioka CE, Akumka D, Ilondu NA. (2001, April), "Ecotoxicological study of the Niger Delta area of River Niger", Bulletin of Environmental Contamination & Toxicology, Vol. 66, (Issue 4), pp 548-552 |
| 38 | Orisakwe OE, Agbasi PU, Afonne OJ, Ofoefule SI, Obi E, Orish CN. (2001, May), "Rifampicin pharmacokinetics with and without ciprofloxacin", American Journal of Therapeutics, Vol. 8, (Issue 3), pp 151-153 |
| 39 | Orisakwe OE, Akumka DD, Afonne OJ, Gamaniel KS, Amos S. (2000, May), "Investigation into the pharmacological basis for some of the folkoric uses of bonny light crude oil in Nigeria", Indian Journal of Pharmacology, Vol. 32, (Issue 3), pp 231-234 |
| 40 | Afonne OJ, Orisakwe OE, Ndubuka GI, Akumka DD, Ilondu N. (2000, March), "Zinc protection of mercury-induced hepatic toxicity in mice", Biological and Pharmaceutical Bulletin, Vol. 23, (Issue 3), pp 305-308 |
| 41 | Afonne OJ, Orisakwe OE., Obi E, Orish CN, Akumka DD. (2000, May), "Some pharmacological properties of Synclisia scabrida III", Indian Journal of Pharmacology, Vol. 32, (Issue 3), pp 239-241 |
| 42 | Orisakwe OE, Ilondu NDA, Afonne OJ, Ofoefule SI, Orish CN. (2000, August), "Acceleration of body clearance of diethylcarbamazine by oral activated charcoal", Pharmacological Research, Vol. 42, (Issue 2), pp 167-170 |
Academic Leadership Qualities
| Editorships | |
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| 1 | Editor, "Asian Toxicology Research" (September, 2021) |
Membership of Professional/Relevant Bodies
| 1 | Full Member, "Society of Toxicology" (member since 2018), https://www.toxicology.org |
| 2 | Full Member, "West African Society of Toxicology" (member since 2016), https://www.wasot.org |